CM4377-3928 Screening compound: (3-{[1-(2-METHOXYETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHOXY}PIPERIDINO)(TETRAHYDRO-2H-PYRAN-4-YL)METHANONE

CM4377-3928 Screening compound: (3-{[1-(2-METHOXYETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHOXY}PIPERIDINO)(TETRAHYDRO-2H-PYRAN-4-YL)METHANONE
CM4377-3928 Screening compound: (3-{[1-(2-METHOXYETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHOXY}PIPERIDINO)(TETRAHYDRO-2H-PYRAN-4-YL)METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound CM4377-3928
(3-{[1-(2-METHOXYETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHOXY}PIPERIDINO)(TETRAHYDRO-2H-PYRAN-4-YL)METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM4377-3928

Molecular Formula

C19H31N3O4 (C19 H31 N3 O4)

Compound Name

(3-{[1-(2-METHOXYETHYL)-5-METHYL-1H-IMIDAZOL-2-YL]METHOXY}PIPERIDINO)(TETRAHYDRO-2H-PYRAN-4-YL)METHANONE

IUPAC name

3-{[1-(2-methoxyethyl)-5-methyl-1H-imidazol-2-yl]methoxy}-1-(oxane-4-carbonyl)piperidine

SMILES

Cc1cnc(COC(CCC2)CN2C(C2CCOCC2)=O)n1CCOC

InChI

InChI=1S/C19H31N3O4/c1-15-12-20-18(22(15)8-11-24-2)14-26-17-4-3-7-21(13-17)19(23)16-5-9-25-10-6-16/h12,16-17H,3-11,13-14H2,1-2H3/t17-/m0/s1

InChI Key

RJSJTCPIPLSZSB-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD30467468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.795

Distribution Coefficient, logD

-0.191

Water Solubility, LogSw

-0.89

Polar Surface Area

52.416

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

8.34

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

78.95

CM4377-3928 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with CM4377-3928 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM4377-3928?
Check Price and Availability of CM4377-3928, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM4377-3928 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM4377-3928
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM4377-3928
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM4377-3928 available by request