CM4667-7337 Screening compound: 8-[5-(3,4-dimethoxyphenyl)-1,3-oxazole-4-carbonyl]-2-(ethoxymethyl)-1-oxa-8-azaspiro[4.5]decane

CM4667-7337 Screening compound: 8-[5-(3,4-dimethoxyphenyl)-1,3-oxazole-4-carbonyl]-2-(ethoxymethyl)-1-oxa-8-azaspiro[4.5]decane
CM4667-7337 Screening compound: 8-[5-(3,4-dimethoxyphenyl)-1,3-oxazole-4-carbonyl]-2-(ethoxymethyl)-1-oxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound CM4667-7337
8-[5-(3,4-dimethoxyphenyl)-1,3-oxazole-4-carbonyl]-2-(ethoxymethyl)-1-oxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM4667-7337

Molecular Formula

C23H30N2O6 (C23 H30 N2 O6)

Compound Name

8-[5-(3,4-dimethoxyphenyl)-1,3-oxazole-4-carbonyl]-2-(ethoxymethyl)-1-oxa-8-azaspiro[4.5]decane

IUPAC name

8-[5-(34-dimethoxyphenyl)-13-oxazole-4-carbonyl]-2-(ethoxymethyl)-1-oxa-8-azaspiro[4.5]decane

SMILES

CCOCC(CC1)OC1(CC1)CCN1C(c1c(-c(cc2)cc(OC)c2OC)ocn1)=O

InChI

InChI=1S/C23H30N2O6/c1-4-29-14-17-7-8-23(31-17)9-11-25(12-10-23)22(26)20-21(30-15-24-20)16-5-6-18(27-2)19(13-16)28-3/h5-6,13,15,17H,4,7-12,14H2,1-3H3/t17-/m0/s1

InChI Key

GXSVWPKNIRFGOS-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD30467558

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.018

Distribution Coefficient, logD

2.018

Water Solubility, LogSw

-2.32

Polar Surface Area

65.369

Acid Dissociation Constant (pKa)

26.69

Base Dissociation Constant (pKb)

-2.32

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

56.52

CM4667-7337 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with CM4667-7337 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM4667-7337?
Check Price and Availability of CM4667-7337, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM4667-7337 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM4667-7337
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM4667-7337
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM4667-7337 available by request