CM4670-0048 Screening compound: N-(3-methoxyphenyl)-2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)-2,8-diazaspiro[4.5]decane-8-carboxamide

CM4670-0048 Screening compound: N-(3-methoxyphenyl)-2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)-2,8-diazaspiro[4.5]decane-8-carboxamide
CM4670-0048 Screening compound: N-(3-methoxyphenyl)-2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)-2,8-diazaspiro[4.5]decane-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound CM4670-0048
N-(3-methoxyphenyl)-2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)-2,8-diazaspiro[4.5]decane-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM4670-0048

Molecular Formula

C20H27N5O3 (C20 H27 N5 O3)

Compound Name

N-(3-methoxyphenyl)-2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)-2,8-diazaspiro[4.5]decane-8-carboxamide

IUPAC name

N-(3-methoxyphenyl)-2-methyl-4-(5-methyl-134-oxadiazol-2-yl)-28-diazaspiro[4.5]decane-8-carboxamide

SMILES

Cc1nnc(C(CN(C)C2)C2(CC2)CCN2C(Nc2cc(OC)ccc2)=O)o1

InChI

InChI=1S/C20H27N5O3/c1-14-22-23-18(28-14)17-12-24(2)13-20(17)7-9-25(10-8-20)19(26)21-15-5-4-6-16(11-15)27-3/h4-6,11,17H,7-10,12-13H2,1-3H3,(H,21,26)/t17-/m1/s1

InChI Key

UQECZVHCSHHLFO-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD30460107

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.366

Distribution Coefficient, logD

-2.148

Water Solubility, LogSw

-2.25

Polar Surface Area

66.625

Acid Dissociation Constant (pKa)

13.05

Base Dissociation Constant (pKb)

10.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.00

CM4670-0048 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with CM4670-0048 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM4670-0048?
Check Price and Availability of CM4670-0048, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM4670-0048 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM4670-0048
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM4670-0048
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM4670-0048 available by request