CM4670A-2824 Screening compound: 8-methyl-4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-2-[3-(trifluoromethyl)benzoyl]-2,8-diazaspiro[4.5]decane

CM4670A-2824 Screening compound: 8-methyl-4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-2-[3-(trifluoromethyl)benzoyl]-2,8-diazaspiro[4.5]decane
CM4670A-2824 Screening compound: 8-methyl-4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-2-[3-(trifluoromethyl)benzoyl]-2,8-diazaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound CM4670A-2824
8-methyl-4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-2-[3-(trifluoromethyl)benzoyl]-2,8-diazaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM4670A-2824

Molecular Formula

C22H27F3N4O2 (C22 H27 F3 N4 O2)

Compound Name

8-methyl-4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-2-[3-(trifluoromethyl)benzoyl]-2,8-diazaspiro[4.5]decane

IUPAC name

8-methyl-4-[5-(propan-2-yl)-134-oxadiazol-2-yl]-2-[3-(trifluoromethyl)benzoyl]-28-diazaspiro[4.5]decane

SMILES

CC(C)c1nnc(C(CN(C2)C(c3cccc(C(F)(F)F)c3)=O)C22CCN(C)CC2)o1

InChI

InChI=1S/C22H27F3N4O2/c1-14(2)18-26-27-19(31-18)17-12-29(13-21(17)7-9-28(3)10-8-21)20(30)15-5-4-6-16(11-15)22(23,24)25/h4-6,11,14,17H,7-10,12-13H2,1-3H3/t17-/m0/s1

InChI Key

ZUXHQXFXIPCXIF-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD30460120

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.762

Distribution Coefficient, logD

0.717

Water Solubility, LogSw

-3.09

Polar Surface Area

51.032

Acid Dissociation Constant (pKa)

25.98

Base Dissociation Constant (pKb)

9.44

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

59.09

CM4670A-2824 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetics of Beta-Turn Motifs Library (2153 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with CM4670A-2824 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM4670A-2824?
Check Price and Availability of CM4670A-2824, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM4670A-2824 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM4670A-2824
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM4670A-2824
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM4670A-2824 available by request