D047-0186 Screening compound: N1'-[4-(propan-2-yl)phenyl]-[1,4'-bipiperidine]-1',4'-dicarboxamide

D047-0186 Screening compound: N1'-[4-(propan-2-yl)phenyl]-[1,4'-bipiperidine]-1',4'-dicarboxamide
D047-0186 Screening compound: N1'-[4-(propan-2-yl)phenyl]-[1,4'-bipiperidine]-1',4'-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D047-0186
N1'-[4-(propan-2-yl)phenyl]-[1,4'-bipiperidine]-1',4'-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D047-0186

Molecular Formula

C21H32N4O2 (C21 H32 N4 O2)

Compound Name

N1'-[4-(propan-2-yl)phenyl]-[1,4'-bipiperidine]-1',4'-dicarboxamide

IUPAC name

N1'-[4-(propan-2-yl)phenyl]-[14'-bipiperidine]-1'4'-dicarboxamide

SMILES

CC(C)c(cc1)ccc1NC(N(CC1)CCC1(C(N)=O)N1CCCCC1)=O

InChI

InChI=1S/C21H32N4O2/c1-16(2)17-6-8-18(9-7-17)23-20(27)24-14-10-21(11-15-24,19(22)26)25-12-4-3-5-13-25/h6-9,16H,3-5,10-15H2,1-2H3,(H2,22,26)(H,23,27)

InChI Key

LXUHSNAPWQETNH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14811509

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.291

Distribution Coefficient, logD

2.449

Water Solubility, LogSw

-3.56

Polar Surface Area

62.843

Acid Dissociation Constant (pKa)

13.90

Base Dissociation Constant (pKb)

8.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.90

D047-0186 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with D047-0186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D047-0186?
Check Price and Availability of D047-0186, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D047-0186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D047-0186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D047-0186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D047-0186 available by request