D060-0152 Screening compound: 5-[1-(3-fluorobenzoyl)piperidin-4-yl]-3-[(2-fluorophenyl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol

D060-0152 Screening compound: 5-[1-(3-fluorobenzoyl)piperidin-4-yl]-3-[(2-fluorophenyl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol
D060-0152 Screening compound: 5-[1-(3-fluorobenzoyl)piperidin-4-yl]-3-[(2-fluorophenyl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound D060-0152
5-[1-(3-fluorobenzoyl)piperidin-4-yl]-3-[(2-fluorophenyl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D060-0152

Molecular Formula

C23H20F2N6O2 (C23 H20 F2 N6 O2)

Compound Name

5-[1-(3-fluorobenzoyl)piperidin-4-yl]-3-[(2-fluorophenyl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol

IUPAC name

5-[1-(3-fluorobenzoyl)piperidin-4-yl]-3-[(2-fluorophenyl)methyl]-3H-[123]triazolo[45-d]pyrimidin-7-ol

SMILES

Oc1c2nnn(Cc(cccc3)c3F)c2nc(C(CC2)CCN2C(c2cc(F)ccc2)=O)n1

InChI

InChI=1S/C23H20F2N6O2/c24-17-6-3-5-15(12-17)23(33)30-10-8-14(9-11-30)20-26-21-19(22(32)27-20)28-29-31(21)13-16-4-1-2-7-18(16)25/h1-7,12,14H,8-11,13H2,(H,26,27,32)

InChI Key

NECCMWHTUIPGLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14811650

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.720

Distribution Coefficient, logD

2.266

Water Solubility, LogSw

-2.82

Polar Surface Area

79.202

Acid Dissociation Constant (pKa)

7.13

Base Dissociation Constant (pKb)

0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

D060-0152 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D060-0152 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D060-0152?
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What is the minimum amount of D060-0152 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D060-0152
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D060-0152
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D060-0152 available by request