D063-0924 Screening compound: 1'-ethyl-6,7-dimethyl-2-[(oxolan-2-yl)methyl]-1',2',3,9-tetrahydro-2H-spiro[chromeno[2,3-c]pyrrole-1,3'-indole]-2',3,9-trione

D063-0924 Screening compound: 1'-ethyl-6,7-dimethyl-2-[(oxolan-2-yl)methyl]-1',2',3,9-tetrahydro-2H-spiro[chromeno[2,3-c]pyrrole-1,3'-indole]-2',3,9-trione
D063-0924 Screening compound: 1'-ethyl-6,7-dimethyl-2-[(oxolan-2-yl)methyl]-1',2',3,9-tetrahydro-2H-spiro[chromeno[2,3-c]pyrrole-1,3'-indole]-2',3,9-trione alternative view

Chemical Structure Depiction of ChemDiv screening compound D063-0924
1'-ethyl-6,7-dimethyl-2-[(oxolan-2-yl)methyl]-1',2',3,9-tetrahydro-2H-spiro[chromeno[2,3-c]pyrrole-1,3'-indole]-2',3,9-trione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D063-0924

Molecular Formula

C27H26N2O5 (C27 H26 N2 O5)

Compound Name

1'-ethyl-6,7-dimethyl-2-[(oxolan-2-yl)methyl]-1',2',3,9-tetrahydro-2H-spiro[chromeno[2,3-c]pyrrole-1,3'-indole]-2',3,9-trione

IUPAC name

1'-ethyl-67-dimethyl-2-[(oxolan-2-yl)methyl]-1'2'39-tetrahydro-2H-spiro[chromeno[23-c]pyrrole-13'-indole]-2'39-trione

SMILES

CCN(C(C1(C2=C3Oc(cc(C)c(C)c4)c4C2=O)N(CC2OCCC2)C3=O)=O)c2c1cccc2

InChI

InChI=1S/C27H26N2O5/c1-4-28-20-10-6-5-9-19(20)27(26(28)32)22-23(30)18-12-15(2)16(3)13-21(18)34-24(22)25(31)29(27)14-17-8-7-11-33-17/h5-6,9-10,12-13,17H,4,7-8,11,14H2,1-3H3

InChI Key

YITDNORCJRJUIA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06648245

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.853

Distribution Coefficient, logD

3.853

Water Solubility, LogSw

-3.99

Polar Surface Area

60.286

Acid Dissociation Constant (pKa)

26.64

Base Dissociation Constant (pKb)

-1.15

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

37.00

D063-0924 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Proteases
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with D063-0924 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D063-0924?
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What is the minimum amount of D063-0924 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D063-0924
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D063-0924
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D063-0924 available by request