D109-0357 Screening compound: N-[4-(3,4-dipropoxyphenyl)-1,2,5-oxadiazol-3-yl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide

D109-0357 Screening compound: N-[4-(3,4-dipropoxyphenyl)-1,2,5-oxadiazol-3-yl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide
D109-0357 Screening compound: N-[4-(3,4-dipropoxyphenyl)-1,2,5-oxadiazol-3-yl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D109-0357
N-[4-(3,4-dipropoxyphenyl)-1,2,5-oxadiazol-3-yl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D109-0357

Molecular Formula

C26H29N3O5 (C26 H29 N3 O5)

Compound Name

N-[4-(3,4-dipropoxyphenyl)-1,2,5-oxadiazol-3-yl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide

IUPAC name

N-[4-(34-dipropoxyphenyl)-125-oxadiazol-3-yl]-356-trimethyl-1-benzofuran-2-carboxamide

SMILES

CCCOc(ccc(-c1nonc1NC(c1c(C)c(cc(C)c(C)c2)c2o1)=O)c1)c1OCCC

InChI

InChI=1S/C26H29N3O5/c1-6-10-31-20-9-8-18(14-22(20)32-11-7-2)23-25(29-34-28-23)27-26(30)24-17(5)19-12-15(3)16(4)13-21(19)33-24/h8-9,12-14H,6-7,10-11H2,1-5H3,(H,27,29,30)

InChI Key

FRHZSPZGIQEUEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06648950

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

7.177

Distribution Coefficient, logD

7.086

Water Solubility, LogSw

-5.71

Polar Surface Area

83.621

Acid Dissociation Constant (pKa)

8.03

Base Dissociation Constant (pKb)

-3.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

D109-0357 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

KRAS-Targeted Library (16000 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D109-0357 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D109-0357?
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What is the minimum amount of D109-0357 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D109-0357
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D109-0357
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D109-0357 available by request