D143-0549 Screening compound: 8-methyl-2,3,4,5,10,11,12,13-octahydro[1]benzofuro[3,2-g]cyclohepta[c]chromen-6(1H)-one

D143-0549 Screening compound: 8-methyl-2,3,4,5,10,11,12,13-octahydro[1]benzofuro[3,2-g]cyclohepta[c]chromen-6(1H)-one
D143-0549 Screening compound: 8-methyl-2,3,4,5,10,11,12,13-octahydro[1]benzofuro[3,2-g]cyclohepta[c]chromen-6(1H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D143-0549
8-methyl-2,3,4,5,10,11,12,13-octahydro[1]benzofuro[3,2-g]cyclohepta[c]chromen-6(1H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D143-0549

Molecular Formula

C21H22O3 (C21 H22 O3)

Compound Name

8-methyl-2,3,4,5,10,11,12,13-octahydro[1]benzofuro[3,2-g]cyclohepta[c]chromen-6(1H)-one

IUPAC name

12-methyl-1014-dioxapentacyclo[11.9.0.0^{311}.0^{49}.0^{1622}]docosa-13(11)4(9)1216(22)-pentaen-15-one

SMILES

Cc1c2oc(CCCC3)c3c2cc(C2=C3CCCCC2)c1OC3=O

InChI

InChI=1S/C21H22O3/c1-12-19-17(14-8-5-6-10-18(14)23-19)11-16-13-7-3-2-4-9-15(13)21(22)24-20(12)16/h11H,2-10H2,1H3

InChI Key

CDYIKZDLVPHZAG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03854243

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

0.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.522

Distribution Coefficient, logD

5.522

Water Solubility, LogSw

-5.47

Polar Surface Area

29.444

Acid Dissociation Constant (pKa)

25.48

Base Dissociation Constant (pKb)

0.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

D143-0549 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D143-0549 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D143-0549?
Check Price and Availability of D143-0549, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D143-0549 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D143-0549
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D143-0549
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D143-0549 available by request