D144-0227 Screening compound: 6-chloro-9-[(3,4-dimethoxyphenyl)methyl]-4-phenyl-2H,8H,9H,10H-chromeno[8,7-e][1,3]oxazin-2-one

D144-0227 Screening compound: 6-chloro-9-[(3,4-dimethoxyphenyl)methyl]-4-phenyl-2H,8H,9H,10H-chromeno[8,7-e][1,3]oxazin-2-one
D144-0227 Screening compound: 6-chloro-9-[(3,4-dimethoxyphenyl)methyl]-4-phenyl-2H,8H,9H,10H-chromeno[8,7-e][1,3]oxazin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D144-0227
6-chloro-9-[(3,4-dimethoxyphenyl)methyl]-4-phenyl-2H,8H,9H,10H-chromeno[8,7-e][1,3]oxazin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D144-0227

Molecular Formula

C26H22ClNO5 (C26 H22 ClNO5)

Compound Name

6-chloro-9-[(3,4-dimethoxyphenyl)methyl]-4-phenyl-2H,8H,9H,10H-chromeno[8,7-e][1,3]oxazin-2-one

IUPAC name

6-chloro-9-[(34-dimethoxyphenyl)methyl]-4-phenyl-2H8H9H10H-chromeno[87-e][13]oxazin-2-one

SMILES

COc(ccc(CN(Cc1c(c(C(c2ccccc2)=C2)c3)OC2=O)COc1c3Cl)c1)c1OC

InChI

InChI=1S/C26H22ClNO5/c1-30-22-9-8-16(10-23(22)31-2)13-28-14-20-25-19(11-21(27)26(20)32-15-28)18(12-24(29)33-25)17-6-4-3-5-7-17/h3-12H,13-15H2,1-2H3

InChI Key

QANAPZVUONELND-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05688836

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.953

Distribution Coefficient, logD

4.812

Water Solubility, LogSw

-5.13

Polar Surface Area

47.588

Acid Dissociation Constant (pKa)

26.35

Base Dissociation Constant (pKb)

6.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

D144-0227 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with D144-0227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D144-0227?
Check Price and Availability of D144-0227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D144-0227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D144-0227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D144-0227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D144-0227 available by request