D144-1105 Screening compound: N-[(3-chlorophenyl)methyl]-3-(7-hydroxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)propanamide

D144-1105 Screening compound: N-[(3-chlorophenyl)methyl]-3-(7-hydroxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)propanamide
D144-1105 Screening compound: N-[(3-chlorophenyl)methyl]-3-(7-hydroxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D144-1105
N-[(3-chlorophenyl)methyl]-3-(7-hydroxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D144-1105

Molecular Formula

C21H20ClNO4 (C21 H20 ClNO4)

Compound Name

N-[(3-chlorophenyl)methyl]-3-(7-hydroxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)propanamide

IUPAC name

N-[(3-chlorophenyl)methyl]-3-(7-hydroxy-48-dimethyl-2-oxo-2H-chromen-3-yl)propanamide

SMILES

Cc(c(O1)c(cc2)C(C)=C(CCC(NCc3cccc(Cl)c3)=O)C1=O)c2O

InChI

InChI=1S/C21H20ClNO4/c1-12-16-6-8-18(24)13(2)20(16)27-21(26)17(12)7-9-19(25)23-11-14-4-3-5-15(22)10-14/h3-6,8,10,24H,7,9,11H2,1-2H3,(H,23,25)

InChI Key

ZMVMOEGNZKHQPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06439710

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.85

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.886

Distribution Coefficient, logD

3.882

Water Solubility, LogSw

-4.02

Polar Surface Area

61.592

Acid Dissociation Constant (pKa)

9.38

Base Dissociation Constant (pKb)

-3.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

D144-1105 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

3D-Biodiversity Library (27607 compounds)

CORONAVIRUS Library (20774 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Structure:
  • 3D

References: we are preparing a list of scientific research reports with D144-1105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D144-1105?
Check Price and Availability of D144-1105, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D144-1105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D144-1105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D144-1105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D144-1105 available by request