D159-0521 Screening compound: 1-(2-fluorophenyl)-6,8-dimethyl-2-[3-(propan-2-yloxy)propyl]-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione

D159-0521 Screening compound: 1-(2-fluorophenyl)-6,8-dimethyl-2-[3-(propan-2-yloxy)propyl]-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione
D159-0521 Screening compound: 1-(2-fluorophenyl)-6,8-dimethyl-2-[3-(propan-2-yloxy)propyl]-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D159-0521
1-(2-fluorophenyl)-6,8-dimethyl-2-[3-(propan-2-yloxy)propyl]-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D159-0521

Molecular Formula

C25H26FNO4 (C25 H26 FNO4)

Compound Name

1-(2-fluorophenyl)-6,8-dimethyl-2-[3-(propan-2-yloxy)propyl]-1H,2H,3H,9H-chromeno[2,3-c]pyrrole-3,9-dione

IUPAC name

1-(2-fluorophenyl)-68-dimethyl-2-[3-(propan-2-yloxy)propyl]-1H2H3H9H-chromeno[23-c]pyrrole-39-dione

SMILES

CC(C)OCCCN(C(C1=C2Oc(cc(C)cc3C)c3C1=O)c(cccc1)c1F)C2=O

InChI

InChI=1S/C25H26FNO4/c1-14(2)30-11-7-10-27-22(17-8-5-6-9-18(17)26)21-23(28)20-16(4)12-15(3)13-19(20)31-24(21)25(27)29/h5-6,8-9,12-14,22H,7,10-11H2,1-4H3/t22-/m1/s1

InChI Key

IZAOKGYIKINRKL-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD06648248

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.815

Distribution Coefficient, logD

4.815

Water Solubility, LogSw

-4.67

Polar Surface Area

44.184

Acid Dissociation Constant (pKa)

18.11

Base Dissociation Constant (pKb)

-5.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.00

D159-0521 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with D159-0521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D159-0521?
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What is the minimum amount of D159-0521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D159-0521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D159-0521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D159-0521 available by request