D165-0378 Screening compound: N-(6-ethyl-7-methyl[1,2,4]triazolo[4,3-a]pyrimidin-5-yl)-N-(3-fluoro-4-methylphenyl)amine

D165-0378 Screening compound: N-(6-ethyl-7-methyl[1,2,4]triazolo[4,3-a]pyrimidin-5-yl)-N-(3-fluoro-4-methylphenyl)amine
D165-0378 Screening compound: N-(6-ethyl-7-methyl[1,2,4]triazolo[4,3-a]pyrimidin-5-yl)-N-(3-fluoro-4-methylphenyl)amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D165-0378
N-(6-ethyl-7-methyl[1,2,4]triazolo[4,3-a]pyrimidin-5-yl)-N-(3-fluoro-4-methylphenyl)amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D165-0378

Molecular Formula

C15H16FN5 (C15 H16 FN5)

Compound Name

N-(6-ethyl-7-methyl[1,2,4]triazolo[4,3-a]pyrimidin-5-yl)-N-(3-fluoro-4-methylphenyl)amine

IUPAC name

6-ethyl-N-(3-fluoro-4-methylphenyl)-7-methyl-[124]triazolo[43-a]pyrimidin-5-amine

SMILES

CCc(c(C)n1)c(Nc2cc(F)c(C)cc2)n2c1nnc2

InChI

InChI=1S/C15H16FN5/c1-4-12-10(3)18-15-20-17-8-21(15)14(12)19-11-6-5-9(2)13(16)7-11/h5-8,19H,4H2,1-3H3

InChI Key

GMFHQFFXCTYMJV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD26967285

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

285.32

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.215

Distribution Coefficient, logD

3.210

Water Solubility, LogSw

-3.09

Polar Surface Area

41.079

Acid Dissociation Constant (pKa)

14.46

Base Dissociation Constant (pKb)

5.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.67

D165-0378 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Fragments Library (11262 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Structure:
  • Fragments

References: we are preparing a list of scientific research reports with D165-0378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D165-0378?
Check Price and Availability of D165-0378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D165-0378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D165-0378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D165-0378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D165-0378 available by request