D174-0355 Screening compound: 2-(2-chlorophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]propanamide

D174-0355 Screening compound: 2-(2-chlorophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]propanamide
D174-0355 Screening compound: 2-(2-chlorophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D174-0355
2-(2-chlorophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D174-0355

Molecular Formula

C23H29ClN2O3 (C23 H29 ClN2 O3)

Compound Name

2-(2-chlorophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]propanamide

IUPAC name

2-(2-chlorophenoxy)-N-[2-(4-methoxyphenyl)-2-(piperidin-1-yl)ethyl]propanamide

SMILES

CC(C(NCC(c(cc1)ccc1OC)N1CCCCC1)=O)Oc(cccc1)c1Cl

InChI

InChI=1S/C23H29ClN2O3/c1-17(29-22-9-5-4-8-20(22)24)23(27)25-16-21(26-14-6-3-7-15-26)18-10-12-19(28-2)13-11-18/h4-5,8-13,17,21H,3,6-7,14-16H2,1-2H3,(H,25,27)

InChI Key

CJDZOPPWEQIDQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07449608

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

416.95

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.515

Distribution Coefficient, logD

3.935

Water Solubility, LogSw

-4.65

Polar Surface Area

42.061

Acid Dissociation Constant (pKa)

12.95

Base Dissociation Constant (pKb)

7.85

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

43.50

D174-0355 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with D174-0355 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D174-0355?
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What is the minimum amount of D174-0355 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D174-0355
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D174-0355
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D174-0355 available by request