D186-0624 Screening compound: N-methyl-N-phenyl-2-{2-[(piperidin-1-yl)methyl]-1H-1,3-benzodiazol-1-yl}acetamide

D186-0624 Screening compound: N-methyl-N-phenyl-2-{2-[(piperidin-1-yl)methyl]-1H-1,3-benzodiazol-1-yl}acetamide
D186-0624 Screening compound: N-methyl-N-phenyl-2-{2-[(piperidin-1-yl)methyl]-1H-1,3-benzodiazol-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D186-0624
N-methyl-N-phenyl-2-{2-[(piperidin-1-yl)methyl]-1H-1,3-benzodiazol-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D186-0624

Molecular Formula

C22H26N4O (C22 H26 N4 O)

Compound Name

N-methyl-N-phenyl-2-{2-[(piperidin-1-yl)methyl]-1H-1,3-benzodiazol-1-yl}acetamide

IUPAC name

N-methyl-N-phenyl-2-{2-[(piperidin-1-yl)methyl]-1H-13-benzodiazol-1-yl}acetamide

SMILES

CN(C(Cn1c(cccc2)c2nc1CN1CCCCC1)=O)c1ccccc1

InChI

InChI=1S/C22H26N4O/c1-24(18-10-4-2-5-11-18)22(27)17-26-20-13-7-6-12-19(20)23-21(26)16-25-14-8-3-9-15-25/h2,4-7,10-13H,3,8-9,14-17H2,1H3

InChI Key

AAWQTHKIXYRLMR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12961966

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.867

Distribution Coefficient, logD

2.645

Water Solubility, LogSw

-2.99

Polar Surface Area

29.989

Acid Dissociation Constant (pKa)

16.27

Base Dissociation Constant (pKb)

7.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

D186-0624 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D186-0624 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D186-0624?
Check Price and Availability of D186-0624, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D186-0624 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D186-0624
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D186-0624
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D186-0624 available by request