D203-0106 Screening compound: 1-(4-{3-[(2-fluorophenyl)methyl]-7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl}piperidin-1-yl)-2-methylpropan-1-one

D203-0106 Screening compound: 1-(4-{3-[(2-fluorophenyl)methyl]-7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl}piperidin-1-yl)-2-methylpropan-1-one
D203-0106 Screening compound: 1-(4-{3-[(2-fluorophenyl)methyl]-7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl}piperidin-1-yl)-2-methylpropan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D203-0106
1-(4-{3-[(2-fluorophenyl)methyl]-7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl}piperidin-1-yl)-2-methylpropan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D203-0106

Molecular Formula

C20H23FN6O2 (C20 H23 FN6 O2)

Compound Name

1-(4-{3-[(2-fluorophenyl)methyl]-7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl}piperidin-1-yl)-2-methylpropan-1-one

IUPAC name

1-(4-{3-[(2-fluorophenyl)methyl]-7-hydroxy-3H-[123]triazolo[45-d]pyrimidin-5-yl}piperidin-1-yl)-2-methylpropan-1-one

SMILES

CC(C)C(N(CC1)CCC1c1nc(O)c2nnn(Cc(cccc3)c3F)c2n1)=O

InChI

InChI=1S/C20H23FN6O2/c1-12(2)20(29)26-9-7-13(8-10-26)17-22-18-16(19(28)23-17)24-25-27(18)11-14-5-3-4-6-15(14)21/h3-6,12-13H,7-11H2,1-2H3,(H,22,23,28)

InChI Key

OWTGDBBEKNYUFZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14813820

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.332

Distribution Coefficient, logD

1.878

Water Solubility, LogSw

-2.40

Polar Surface Area

79.474

Acid Dissociation Constant (pKa)

7.13

Base Dissociation Constant (pKb)

0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

D203-0106 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Immune system
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D203-0106 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D203-0106?
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What is the minimum amount of D203-0106 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D203-0106
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D203-0106
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D203-0106 available by request