D205-0251 Screening compound: N-{6-chloro-7-hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}thiophene-2-carboxamide

D205-0251 Screening compound: N-{6-chloro-7-hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}thiophene-2-carboxamide
D205-0251 Screening compound: N-{6-chloro-7-hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D205-0251
N-{6-chloro-7-hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D205-0251

Molecular Formula

C11H8ClN5O2S (C11 H8 ClN5 O2 S)

Compound Name

N-{6-chloro-7-hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}thiophene-2-carboxamide

IUPAC name

N-{6-chloro-7-hydroxy-5-methyl-[124]triazolo[15-a]pyrimidin-2-yl}thiophene-2-carboxamide

SMILES

Cc1nc2nc(NC(c3cccs3)=O)nn2c(O)c1Cl

InChI

InChI=1S/C11H8ClN5O2S/c1-5-7(12)9(19)17-11(13-5)15-10(16-17)14-8(18)6-3-2-4-20-6/h2-4,19H,1H3,(H,14,16,18)

InChI Key

DUXWBPOMVYISTL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08069894

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

309.74

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.557

Distribution Coefficient, logD

-1.122

Water Solubility, LogSw

-2.75

Polar Surface Area

72.051

Acid Dissociation Constant (pKa)

4.72

Base Dissociation Constant (pKb)

1.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

D205-0251 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D205-0251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D205-0251?
Check Price and Availability of D205-0251, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D205-0251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D205-0251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D205-0251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D205-0251 available by request