D205-0295 Screening compound: N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}furan-2-carboxamide

D205-0295 Screening compound: N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}furan-2-carboxamide
D205-0295 Screening compound: N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D205-0295
N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D205-0295

Molecular Formula

C12H11N5O3 (C12 H11 N5 O3)

Compound Name

N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}furan-2-carboxamide

IUPAC name

N-{7-hydroxy-56-dimethyl-[124]triazolo[15-a]pyrimidin-2-yl}furan-2-carboxamide

SMILES

Cc(c(C)nc1nc(NC(c2ccco2)=O)nn11)c1O

InChI

InChI=1S/C12H11N5O3/c1-6-7(2)13-12-15-11(16-17(12)10(6)19)14-9(18)8-4-3-5-20-8/h3-5,19H,1-2H3,(H,14,16,18)

InChI Key

TWAZJKOAAOREBH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07793468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

273.25

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.642

Distribution Coefficient, logD

-0.092

Water Solubility, LogSw

-1.54

Polar Surface Area

79.611

Acid Dissociation Constant (pKa)

6.75

Base Dissociation Constant (pKb)

1.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

D205-0295 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

Dark Chemical Matter Library (18430 compounds)

Purinergic Library (3321 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Pool
Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • Kinases
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D205-0295 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D205-0295?
Check Price and Availability of D205-0295, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D205-0295 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D205-0295
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D205-0295
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D205-0295 available by request