D205-0305 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}propanamide

D205-0305 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}propanamide
D205-0305 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D205-0305
2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D205-0305

Molecular Formula

C18H16N6O4 (C18 H16 N6 O4)

Compound Name

2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{7-hydroxy-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}propanamide

IUPAC name

2-(13-dioxo-23-dihydro-1H-isoindol-2-yl)-N-{7-hydroxy-56-dimethyl-[124]triazolo[15-a]pyrimidin-2-yl}propanamide

SMILES

CC(C(Nc1nn2c(O)c(C)c(C)nc2n1)=O)N(C(c1c2cccc1)=O)C2=O

InChI

InChI=1S/C18H16N6O4/c1-8-9(2)19-18-21-17(22-24(18)14(8)26)20-13(25)10(3)23-15(27)11-6-4-5-7-12(11)16(23)28/h4-7,10,26H,1-3H3,(H,20,22,25)/t10-/m0/s1

InChI Key

XPGPCBMRVSHIEX-JTQLQIEISA-N

MDL Number (MFCD)

MFCD14813985

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.36

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.109

Distribution Coefficient, logD

0.374

Water Solubility, LogSw

-2.06

Polar Surface Area

99.898

Acid Dissociation Constant (pKa)

6.75

Base Dissociation Constant (pKb)

1.38

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

D205-0305 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with D205-0305 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D205-0305?
Check Price and Availability of D205-0305, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D205-0305 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D205-0305
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D205-0305
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D205-0305 available by request