D205-0486 Screening compound: N-{7-hydroxy-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}pyridine-3-carboxamide

D205-0486 Screening compound: N-{7-hydroxy-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}pyridine-3-carboxamide
D205-0486 Screening compound: N-{7-hydroxy-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D205-0486
N-{7-hydroxy-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D205-0486

Molecular Formula

C17H12N6O2 (C17 H12 N6 O2)

Compound Name

N-{7-hydroxy-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}pyridine-3-carboxamide

IUPAC name

N-{7-hydroxy-5-phenyl-[124]triazolo[15-a]pyrimidin-2-yl}pyridine-3-carboxamide

SMILES

Oc1cc(-c2ccccc2)nc2nc(NC(c3cnccc3)=O)nn12

InChI

InChI=1S/C17H12N6O2/c24-14-9-13(11-5-2-1-3-6-11)19-17-21-16(22-23(14)17)20-15(25)12-7-4-8-18-10-12/h1-10,24H,(H,20,22,25)

InChI Key

GVTXVKMYQQBAHU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14814060

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

332.32

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.690

Distribution Coefficient, logD

-0.009

Water Solubility, LogSw

-1.83

Polar Surface Area

80.996

Acid Dissociation Constant (pKa)

5.71

Base Dissociation Constant (pKb)

4.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

D205-0486 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D205-0486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D205-0486?
Check Price and Availability of D205-0486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D205-0486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D205-0486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D205-0486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D205-0486 available by request