D206-0230 Screening compound: 1-[4-(4-chlorobenzenesulfonyl)-2-(4-methylbenzenesulfonyl)-1,3-thiazol-5-yl]piperidin-4-ol

D206-0230 Screening compound: 1-[4-(4-chlorobenzenesulfonyl)-2-(4-methylbenzenesulfonyl)-1,3-thiazol-5-yl]piperidin-4-ol
D206-0230 Screening compound: 1-[4-(4-chlorobenzenesulfonyl)-2-(4-methylbenzenesulfonyl)-1,3-thiazol-5-yl]piperidin-4-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound D206-0230
1-[4-(4-chlorobenzenesulfonyl)-2-(4-methylbenzenesulfonyl)-1,3-thiazol-5-yl]piperidin-4-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D206-0230

Molecular Formula

C21H21ClN2O5S3 (C21 H21 ClN2 O5 S3)

Compound Name

1-[4-(4-chlorobenzenesulfonyl)-2-(4-methylbenzenesulfonyl)-1,3-thiazol-5-yl]piperidin-4-ol

IUPAC name

1-[4-(4-chlorobenzenesulfonyl)-2-(4-methylbenzenesulfonyl)-13-thiazol-5-yl]piperidin-4-ol

SMILES

Cc(cc1)ccc1S(c1nc(S(c(cc2)ccc2Cl)(=O)=O)c(N(CC2)CCC2O)s1)(=O)=O

InChI

InChI=1S/C21H21ClN2O5S3/c1-14-2-6-18(7-3-14)32(28,29)21-23-19(20(30-21)24-12-10-16(25)11-13-24)31(26,27)17-8-4-15(22)5-9-17/h2-9,16,25H,10-13H2,1H3

InChI Key

LFBPKWOPHQBAQF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12966623

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

513.06

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.306

Distribution Coefficient, logD

4.306

Water Solubility, LogSw

-4.22

Polar Surface Area

88.791

Acid Dissociation Constant (pKa)

17.59

Base Dissociation Constant (pKb)

-7.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

D206-0230 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D206-0230 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D206-0230?
Check Price and Availability of D206-0230, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D206-0230 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D206-0230
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D206-0230
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D206-0230 available by request