D216-0248 Screening compound: 2-{4-[4-(1H-1,2,3,4-tetrazol-1-yl)benzenesulfonyl]piperazin-1-yl}pyrimidine

D216-0248 Screening compound: 2-{4-[4-(1H-1,2,3,4-tetrazol-1-yl)benzenesulfonyl]piperazin-1-yl}pyrimidine
D216-0248 Screening compound: 2-{4-[4-(1H-1,2,3,4-tetrazol-1-yl)benzenesulfonyl]piperazin-1-yl}pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound D216-0248
2-{4-[4-(1H-1,2,3,4-tetrazol-1-yl)benzenesulfonyl]piperazin-1-yl}pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D216-0248

Molecular Formula

C15H16N8O2S (C15 H16 N8 O2 S)

Compound Name

2-{4-[4-(1H-1,2,3,4-tetrazol-1-yl)benzenesulfonyl]piperazin-1-yl}pyrimidine

IUPAC name

2-{4-[4-(1H-1234-tetrazol-1-yl)benzenesulfonyl]piperazin-1-yl}pyrimidine

SMILES

O=S(c(cc1)ccc1-n1nnnc1)(N(CC1)CCN1c1ncccn1)=O

InChI

InChI=1S/C15H16N8O2S/c24-26(25,14-4-2-13(3-5-14)23-12-18-19-20-23)22-10-8-21(9-11-22)15-16-6-1-7-17-15/h1-7,12H,8-11H2

InChI Key

GREBJAWIVFTPRG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05245140

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.41

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.431

Distribution Coefficient, logD

1.431

Water Solubility, LogSw

-2.37

Polar Surface Area

93.337

Acid Dissociation Constant (pKa)

20.87

Base Dissociation Constant (pKb)

3.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

D216-0248 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Nuclear receptors
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D216-0248 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D216-0248?
Check Price and Availability of D216-0248, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D216-0248 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D216-0248
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D216-0248
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D216-0248 available by request