D232-0182 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3,5,6-trimethyl-N-[(oxolan-2-yl)methyl]-1-benzofuran-2-carboxamide

D232-0182 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3,5,6-trimethyl-N-[(oxolan-2-yl)methyl]-1-benzofuran-2-carboxamide
D232-0182 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3,5,6-trimethyl-N-[(oxolan-2-yl)methyl]-1-benzofuran-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D232-0182
N-{[4-(dimethylamino)phenyl]methyl}-3,5,6-trimethyl-N-[(oxolan-2-yl)methyl]-1-benzofuran-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D232-0182

Molecular Formula

C26H32N2O3 (C26 H32 N2 O3)

Compound Name

N-{[4-(dimethylamino)phenyl]methyl}-3,5,6-trimethyl-N-[(oxolan-2-yl)methyl]-1-benzofuran-2-carboxamide

IUPAC name

N-{[4-(dimethylamino)phenyl]methyl}-356-trimethyl-N-[(oxolan-2-yl)methyl]-1-benzofuran-2-carboxamide

SMILES

Cc1c(C(N(CC2OCCC2)Cc(cc2)ccc2N(C)C)=O)oc2c1cc(C)c(C)c2

InChI

InChI=1S/C26H32N2O3/c1-17-13-23-19(3)25(31-24(23)14-18(17)2)26(29)28(16-22-7-6-12-30-22)15-20-8-10-21(11-9-20)27(4)5/h8-11,13-14,22H,6-7,12,15-16H2,1-5H3/t22-/m1/s1

InChI Key

ZMQUHGLTJWQRMB-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD07426854

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.100

Distribution Coefficient, logD

5.084

Water Solubility, LogSw

-4.97

Polar Surface Area

36.163

Acid Dissociation Constant (pKa)

26.56

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.30

D232-0182 in Drug Discovery

Included in Screening Libraries

Human Proteases Annotated Library (2868 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Targeted Diversity Library (40567 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with D232-0182 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D232-0182?
Check Price and Availability of D232-0182, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D232-0182 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D232-0182
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D232-0182
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D232-0182 available by request