D244-0208 Screening compound: 5-chloro-N-(2,5-dimethylphenyl)-2-[(2-methylphenyl)methanesulfonyl]pyrimidine-4-carboxamide

D244-0208 Screening compound: 5-chloro-N-(2,5-dimethylphenyl)-2-[(2-methylphenyl)methanesulfonyl]pyrimidine-4-carboxamide
D244-0208 Screening compound: 5-chloro-N-(2,5-dimethylphenyl)-2-[(2-methylphenyl)methanesulfonyl]pyrimidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D244-0208
5-chloro-N-(2,5-dimethylphenyl)-2-[(2-methylphenyl)methanesulfonyl]pyrimidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D244-0208

Molecular Formula

C21H20ClN3O3S (C21 H20 ClN3 O3 S)

Compound Name

5-chloro-N-(2,5-dimethylphenyl)-2-[(2-methylphenyl)methanesulfonyl]pyrimidine-4-carboxamide

IUPAC name

5-chloro-N-(25-dimethylphenyl)-2-[(2-methylphenyl)methanesulfonyl]pyrimidine-4-carboxamide

SMILES

Cc1cc(NC(c(nc(nc2)S(Cc3c(C)cccc3)(=O)=O)c2Cl)=O)c(C)cc1

InChI

InChI=1S/C21H20ClN3O3S/c1-13-8-9-15(3)18(10-13)24-20(26)19-17(22)11-23-21(25-19)29(27,28)12-16-7-5-4-6-14(16)2/h4-11H,12H2,1-3H3,(H,24,26)

InChI Key

YMJJBIOUFQJTET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07454912

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.93

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.649

Distribution Coefficient, logD

4.633

Water Solubility, LogSw

-4.72

Polar Surface Area

70.810

Acid Dissociation Constant (pKa)

8.83

Base Dissociation Constant (pKb)

-2.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

D244-0208 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D244-0208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D244-0208?
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What is the minimum amount of D244-0208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D244-0208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D244-0208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D244-0208 available by request