D245-0210 Screening compound: ethyl 1-[2-(4-tert-butylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxylate

D245-0210 Screening compound: ethyl 1-[2-(4-tert-butylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxylate
D245-0210 Screening compound: ethyl 1-[2-(4-tert-butylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D245-0210
ethyl 1-[2-(4-tert-butylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D245-0210

Molecular Formula

C24H31N5O2 (C24 H31 N5 O2)

Compound Name

ethyl 1-[2-(4-tert-butylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carboxylate

IUPAC name

ethyl 1-[2-(4-tert-butylphenyl)-5-methyl-[124]triazolo[15-a]pyrimidin-7-yl]piperidine-4-carboxylate

SMILES

CCOC(C(CC1)CCN1c1cc(C)nc2nc(-c3ccc(C(C)(C)C)cc3)nn12)=O

InChI

InChI=1S/C24H31N5O2/c1-6-31-22(30)18-11-13-28(14-12-18)20-15-16(2)25-23-26-21(27-29(20)23)17-7-9-19(10-8-17)24(3,4)5/h7-10,15,18H,6,11-14H2,1-5H3

InChI Key

YGQAAVZTBVRISY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14815203

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.514

Distribution Coefficient, logD

5.291

Water Solubility, LogSw

-5.35

Polar Surface Area

53.871

Acid Dissociation Constant (pKa)

22.84

Base Dissociation Constant (pKb)

7.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

D245-0210 in Drug Discovery

Included in Screening Libraries

Purinergic Library (3321 compounds)

Akt-Targeted Library (14764 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Kinases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D245-0210 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D245-0210?
Check Price and Availability of D245-0210, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D245-0210 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D245-0210
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D245-0210
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D245-0210 available by request