D257-0754 Screening compound: 3-[4-(4-methoxyphenyl)piperazino]-1H-1,2-benzisothiazole-1,1-dione

D257-0754 Screening compound: 3-[4-(4-methoxyphenyl)piperazino]-1H-1,2-benzisothiazole-1,1-dione
D257-0754 Screening compound: 3-[4-(4-methoxyphenyl)piperazino]-1H-1,2-benzisothiazole-1,1-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D257-0754
3-[4-(4-methoxyphenyl)piperazino]-1H-1,2-benzisothiazole-1,1-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D257-0754

Molecular Formula

C18H19N3O3S (C18 H19 N3 O3 S)

Compound Name

3-[4-(4-methoxyphenyl)piperazino]-1H-1,2-benzisothiazole-1,1-dione

IUPAC name

3-[4-(4-methoxyphenyl)piperazin-1-yl]-1lambda62-benzothiazole-11-dione

SMILES

COc(cc1)ccc1N(CC1)CCN1C(c1c2cccc1)=NS2(=O)=O

InChI

InChI=1S/C18H19N3O3S/c1-24-15-8-6-14(7-9-15)20-10-12-21(13-11-20)18-16-4-2-3-5-17(16)25(22,23)19-18/h2-9H,10-13H2,1H3

InChI Key

QUAHVFHLOVQIGY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06381996

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.535

Distribution Coefficient, logD

2.535

Water Solubility, LogSw

-2.83

Polar Surface Area

53.934

Acid Dissociation Constant (pKa)

28.39

Base Dissociation Constant (pKb)

2.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

D257-0754 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antiviral Library (67538 compounds)

BRD4 Targeted Library (4534 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Epigenetic
Targets:
  • Others
  • Others

References: we are preparing a list of scientific research reports with D257-0754 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D257-0754?
Check Price and Availability of D257-0754, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D257-0754 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D257-0754
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D257-0754
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D257-0754 available by request