D264-0018 Screening compound: 1-(pyrimidin-2-yl)-N-{[3-(trifluoromethyl)phenyl]methyl}piperidine-4-carboxamide

D264-0018 Screening compound: 1-(pyrimidin-2-yl)-N-{[3-(trifluoromethyl)phenyl]methyl}piperidine-4-carboxamide
D264-0018 Screening compound: 1-(pyrimidin-2-yl)-N-{[3-(trifluoromethyl)phenyl]methyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D264-0018
1-(pyrimidin-2-yl)-N-{[3-(trifluoromethyl)phenyl]methyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D264-0018

Molecular Formula

C18H19F3N4O (C18 H19 F3 N4 O)

Compound Name

1-(pyrimidin-2-yl)-N-{[3-(trifluoromethyl)phenyl]methyl}piperidine-4-carboxamide

IUPAC name

1-(pyrimidin-2-yl)-N-{[3-(trifluoromethyl)phenyl]methyl}piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1ncccn1)NCc1cccc(C(F)(F)F)c1

InChI

InChI=1S/C18H19F3N4O/c19-18(20,21)15-4-1-3-13(11-15)12-24-16(26)14-5-9-25(10-6-14)17-22-7-2-8-23-17/h1-4,7-8,11,14H,5-6,9-10,12H2,(H,24,26)

InChI Key

ZFHFTXMVCGJOEO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03860159

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.914

Distribution Coefficient, logD

2.913

Water Solubility, LogSw

-3.24

Polar Surface Area

46.466

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

9.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

D264-0018 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CORONAVIRUS Library (20774 compounds)

PI3K-Targeted Library (17255 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D264-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D264-0018?
Check Price and Availability of D264-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D264-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D264-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D264-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D264-0018 available by request