D264-0068 Screening compound: N-[(4-fluorophenyl)methyl]-1-[1-(prop-2-en-1-yl)-1H-1,3-benzodiazol-2-yl]piperidine-4-carboxamide

D264-0068 Screening compound: N-[(4-fluorophenyl)methyl]-1-[1-(prop-2-en-1-yl)-1H-1,3-benzodiazol-2-yl]piperidine-4-carboxamide
D264-0068 Screening compound: N-[(4-fluorophenyl)methyl]-1-[1-(prop-2-en-1-yl)-1H-1,3-benzodiazol-2-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D264-0068
N-[(4-fluorophenyl)methyl]-1-[1-(prop-2-en-1-yl)-1H-1,3-benzodiazol-2-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D264-0068

Molecular Formula

C23H25FN4O (C23 H25 FN4 O)

Compound Name

N-[(4-fluorophenyl)methyl]-1-[1-(prop-2-en-1-yl)-1H-1,3-benzodiazol-2-yl]piperidine-4-carboxamide

IUPAC name

N-[(4-fluorophenyl)methyl]-1-[1-(prop-2-en-1-yl)-1H-13-benzodiazol-2-yl]piperidine-4-carboxamide

SMILES

C=CCn1c(N(CC2)CCC2C(NCc(cc2)ccc2F)=O)nc2c1cccc2

InChI

InChI=1S/C23H25FN4O/c1-2-13-28-21-6-4-3-5-20(21)26-23(28)27-14-11-18(12-15-27)22(29)25-16-17-7-9-19(24)10-8-17/h2-10,18H,1,11-16H2,(H,25,29)

InChI Key

IIUSEORIEMHUET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14815732

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.48

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.955

Distribution Coefficient, logD

3.948

Water Solubility, LogSw

-4.00

Polar Surface Area

37.824

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

5.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

D264-0068 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Targets:
  • Kinases
  • Kinases
  • Proteases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D264-0068 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D264-0068?
Check Price and Availability of D264-0068, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D264-0068 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D264-0068
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D264-0068
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D264-0068 available by request