D264-0108 Screening compound: 1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]piperazine

D264-0108 Screening compound: 1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]piperazine
D264-0108 Screening compound: 1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound D264-0108
1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D264-0108

Molecular Formula

C15H14FN5S (C15 H14 FN5 S)

Compound Name

1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]piperazine

IUPAC name

1-[3-(4-fluorophenyl)-[12]thiazolo[45-d]pyrimidin-7-yl]piperazine

SMILES

Fc(cc1)ccc1-c1nsc2c(N3CCNCC3)ncnc12

InChI

InChI=1S/C15H14FN5S/c16-11-3-1-10(2-4-11)12-13-14(22-20-12)15(19-9-18-13)21-7-5-17-6-8-21/h1-4,9,17H,5-8H2

InChI Key

LESURAYUJPQMLK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03751730

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

315.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.567

Distribution Coefficient, logD

1.324

Water Solubility, LogSw

-2.55

Polar Surface Area

46.870

Acid Dissociation Constant (pKa)

22.29

Base Dissociation Constant (pKb)

8.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

D264-0108 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Immune system
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D264-0108 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D264-0108?
Check Price and Availability of D264-0108, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D264-0108 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D264-0108
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D264-0108
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D264-0108 available by request