D264-0161 Screening compound: 1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]-4-phenylpiperazine

D264-0161 Screening compound: 1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]-4-phenylpiperazine
D264-0161 Screening compound: 1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound D264-0161
1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D264-0161

Molecular Formula

C21H18FN5S (C21 H18 FN5 S)

Compound Name

1-[3-(4-fluorophenyl)-[1,2]thiazolo[4,5-d]pyrimidin-7-yl]-4-phenylpiperazine

IUPAC name

1-[3-(4-fluorophenyl)-[12]thiazolo[45-d]pyrimidin-7-yl]-4-phenylpiperazine

SMILES

Fc(cc1)ccc1-c1nsc2c(N(CC3)CCN3c3ccccc3)ncnc12

InChI

InChI=1S/C21H18FN5S/c22-16-8-6-15(7-9-16)18-19-20(28-25-18)21(24-14-23-19)27-12-10-26(11-13-27)17-4-2-1-3-5-17/h1-9,14H,10-13H2

InChI Key

LPDBJXNQVZMVEQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06011989

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.47

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.910

Distribution Coefficient, logD

4.907

Water Solubility, LogSw

-4.94

Polar Surface Area

38.170

Acid Dissociation Constant (pKa)

22.10

Base Dissociation Constant (pKb)

5.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

D264-0161 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Angiogenesis library (14822 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D264-0161 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D264-0161?
Check Price and Availability of D264-0161, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D264-0161 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D264-0161
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D264-0161
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D264-0161 available by request