D264-0167 Screening compound: N-benzyl-3-(4-fluorophenyl)-N-methyl-[1,2]thiazolo[4,5-d]pyrimidin-7-amine

D264-0167 Screening compound: N-benzyl-3-(4-fluorophenyl)-N-methyl-[1,2]thiazolo[4,5-d]pyrimidin-7-amine
D264-0167 Screening compound: N-benzyl-3-(4-fluorophenyl)-N-methyl-[1,2]thiazolo[4,5-d]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D264-0167
N-benzyl-3-(4-fluorophenyl)-N-methyl-[1,2]thiazolo[4,5-d]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D264-0167

Molecular Formula

C19H15FN4S (C19 H15 FN4 S)

Compound Name

N-benzyl-3-(4-fluorophenyl)-N-methyl-[1,2]thiazolo[4,5-d]pyrimidin-7-amine

IUPAC name

N-benzyl-3-(4-fluorophenyl)-N-methyl-[12]thiazolo[45-d]pyrimidin-7-amine

SMILES

CN(Cc1ccccc1)c(ncnc12)c1snc2-c(cc1)ccc1F

InChI

InChI=1S/C19H15FN4S/c1-24(11-13-5-3-2-4-6-13)19-18-17(21-12-22-19)16(23-25-18)14-7-9-15(20)10-8-14/h2-10,12H,11H2,1H3

InChI Key

POFBOUBSFPMSAU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14815770

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.42

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.802

Distribution Coefficient, logD

4.798

Water Solubility, LogSw

-4.66

Polar Surface Area

34.412

Acid Dissociation Constant (pKa)

21.01

Base Dissociation Constant (pKb)

5.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

D264-0167 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Immune system
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D264-0167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D264-0167?
Check Price and Availability of D264-0167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D264-0167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D264-0167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D264-0167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D264-0167 available by request