D264-1018 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-[(1-cyclopentylpyrrolidin-3-yl)methyl]urea

D264-1018 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-[(1-cyclopentylpyrrolidin-3-yl)methyl]urea
D264-1018 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-[(1-cyclopentylpyrrolidin-3-yl)methyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound D264-1018
1-(5-chloro-2,4-dimethoxyphenyl)-3-[(1-cyclopentylpyrrolidin-3-yl)methyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D264-1018

Molecular Formula

C19H28ClN3O3 (C19 H28 ClN3 O3)

Compound Name

1-(5-chloro-2,4-dimethoxyphenyl)-3-[(1-cyclopentylpyrrolidin-3-yl)methyl]urea

IUPAC name

1-(5-chloro-24-dimethoxyphenyl)-3-[(1-cyclopentylpyrrolidin-3-yl)methyl]urea

SMILES

COc(c(NC(NCC(CC1)CN1C1CCCC1)=O)c1)cc(OC)c1Cl

InChI

InChI=1S/C19H28ClN3O3/c1-25-17-10-18(26-2)16(9-15(17)20)22-19(24)21-11-13-7-8-23(12-13)14-5-3-4-6-14/h9-10,13-14H,3-8,11-12H2,1-2H3,(H2,21,22,24)/t13-/m1/s1

InChI Key

CJOWRXZYAFNDGO-CYBMUJFWSA-N

MDL Number (MFCD)

MFCD14816101

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.9

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.329

Distribution Coefficient, logD

-1.050

Water Solubility, LogSw

-3.72

Polar Surface Area

52.377

Acid Dissociation Constant (pKa)

10.17

Base Dissociation Constant (pKb)

11.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

63.20

D264-1018 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D264-1018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D264-1018?
Check Price and Availability of D264-1018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D264-1018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D264-1018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D264-1018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D264-1018 available by request