D265-0138 Screening compound: N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2,4-dimethyl-1,3-thiazole-5-carboxamide
Chemical Structure Depiction of ChemDiv screening compound D265-0138
N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2,4-dimethyl-1,3-thiazole-5-carboxamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
D265-0138
Molecular Formula
C21H17N3OS2 (C21 H17 N3 OS2)
Compound Name
N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2,4-dimethyl-1,3-thiazole-5-carboxamide
IUPAC name
N-(4-{[11'-biphenyl]-4-yl}-13-thiazol-2-yl)-24-dimethyl-13-thiazole-5-carboxamide
SMILES
Cc1c(C(Nc2nc(-c(cc3)ccc3-c3ccccc3)cs2)=O)sc(C)n1
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
391.52
Hydrogen Bond Acceptors Count
4.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
5.00
Number of Nitrogen and Oxygen Atoms
4
Partition Coefficient, logP
6.078
Distribution Coefficient, logD
6.078
Water Solubility, LogSw
-5.78
Polar Surface Area
43.222
Acid Dissociation Constant (pKa)
10.12
Base Dissociation Constant (pKb)
1.35
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
9.50
D265-0138 in Drug Discovery
Included in Screening Libraries
Allosteric Kinases Inhibitors Library (23117 compounds)
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
Serine Proteases Inhibitors Library (32732 compounds)
SmartTM Library (51161 compounds)
Epigenetics Focused Set (26518 compounds)
Type II Kinase Inhibitors Library (6956 compounds)
Included in 1.7M Stock Database
- Cancer
- Female
- Congenital
- Skin
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- Digestive system
- Hemic and lymphatic
- Endocrine
- Kinases
- Proteases
- Kinases
References: we are preparing a list of scientific research reports with D265-0138 chemical compound. It will be published here after verification.
Frequently Asked Questions
Check Price and Availability of D265-0138, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)