D265-0148 Screening compound: 4-ethyl 2-propan-2-yl 5-(2,4-dimethyl-1,3-thiazole-5-amido)-3-methylthiophene-2,4-dicarboxylate

D265-0148 Screening compound: 4-ethyl 2-propan-2-yl 5-(2,4-dimethyl-1,3-thiazole-5-amido)-3-methylthiophene-2,4-dicarboxylate
D265-0148 Screening compound: 4-ethyl 2-propan-2-yl 5-(2,4-dimethyl-1,3-thiazole-5-amido)-3-methylthiophene-2,4-dicarboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D265-0148
4-ethyl 2-propan-2-yl 5-(2,4-dimethyl-1,3-thiazole-5-amido)-3-methylthiophene-2,4-dicarboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D265-0148

Molecular Formula

C18H22N2O5S2 (C18 H22 N2 O5 S2)

Compound Name

4-ethyl 2-propan-2-yl 5-(2,4-dimethyl-1,3-thiazole-5-amido)-3-methylthiophene-2,4-dicarboxylate

IUPAC name

4-ethyl 2-propan-2-yl 5-(24-dimethyl-13-thiazole-5-amido)-3-methylthiophene-24-dicarboxylate

SMILES

CCOC(c1c(NC(c2c(C)nc(C)s2)=O)sc(C(OC(C)C)=O)c1C)=O

InChI

InChI=1S/C18H22N2O5S2/c1-7-24-17(22)12-9(4)13(18(23)25-8(2)3)27-16(12)20-15(21)14-10(5)19-11(6)26-14/h8H,7H2,1-6H3,(H,20,21)

InChI Key

CVNPAYKVFXSFOX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09541034

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.670

Distribution Coefficient, logD

0.088

Water Solubility, LogSw

-4.09

Polar Surface Area

74.699

Acid Dissociation Constant (pKa)

3.82

Base Dissociation Constant (pKb)

0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

D265-0148 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D265-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D265-0148?
Check Price and Availability of D265-0148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D265-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D265-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D265-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D265-0148 available by request