D265-0325 Screening compound: N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2-(2-methyl-1,3-thiazol-4-yl)acetamide

D265-0325 Screening compound: N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2-(2-methyl-1,3-thiazol-4-yl)acetamide
D265-0325 Screening compound: N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2-(2-methyl-1,3-thiazol-4-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D265-0325
N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2-(2-methyl-1,3-thiazol-4-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D265-0325

Molecular Formula

C21H17N3OS2 (C21 H17 N3 OS2)

Compound Name

N-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-2-(2-methyl-1,3-thiazol-4-yl)acetamide

IUPAC name

N-(4-{[11'-biphenyl]-4-yl}-13-thiazol-2-yl)-2-(2-methyl-13-thiazol-4-yl)acetamide

SMILES

Cc1nc(CC(Nc2nc(-c(cc3)ccc3-c3ccccc3)cs2)=O)cs1

InChI

InChI=1S/C21H17N3OS2/c1-14-22-18(12-26-14)11-20(25)24-21-23-19(13-27-21)17-9-7-16(8-10-17)15-5-3-2-4-6-15/h2-10,12-13H,11H2,1H3,(H,23,24,25)

InChI Key

NFQCGRGCYXGUQC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08568239

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.783

Distribution Coefficient, logD

5.783

Water Solubility, LogSw

-5.76

Polar Surface Area

42.927

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

0.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

D265-0325 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Epigenetics Focused Set (26518 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Proteases
  • Ion Channels
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D265-0325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D265-0325?
Check Price and Availability of D265-0325, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D265-0325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D265-0325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D265-0325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D265-0325 available by request