D266-0498 Screening compound: ethyl 4-methyl-2-(2-methyl-3-oxo-5,6-diphenyl-2,3-dihydropyridazine-4-amido)-1,3-thiazole-5-carboxylate

D266-0498 Screening compound: ethyl 4-methyl-2-(2-methyl-3-oxo-5,6-diphenyl-2,3-dihydropyridazine-4-amido)-1,3-thiazole-5-carboxylate
D266-0498 Screening compound: ethyl 4-methyl-2-(2-methyl-3-oxo-5,6-diphenyl-2,3-dihydropyridazine-4-amido)-1,3-thiazole-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D266-0498
ethyl 4-methyl-2-(2-methyl-3-oxo-5,6-diphenyl-2,3-dihydropyridazine-4-amido)-1,3-thiazole-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D266-0498

Molecular Formula

C25H22N4O4S (C25 H22 N4 O4 S)

Compound Name

ethyl 4-methyl-2-(2-methyl-3-oxo-5,6-diphenyl-2,3-dihydropyridazine-4-amido)-1,3-thiazole-5-carboxylate

IUPAC name

ethyl 4-methyl-2-(2-methyl-3-oxo-56-diphenyl-23-dihydropyridazine-4-amido)-13-thiazole-5-carboxylate

SMILES

CCOC(c1c(C)nc(NC(C2=C(c3ccccc3)C(c3ccccc3)=NN(C)C2=O)=O)s1)=O

InChI

InChI=1S/C25H22N4O4S/c1-4-33-24(32)21-15(2)26-25(34-21)27-22(30)19-18(16-11-7-5-8-12-16)20(28-29(3)23(19)31)17-13-9-6-10-14-17/h5-14H,4H2,1-3H3,(H,26,27,30)

InChI Key

GAHXUWBQXFSULF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09057901

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.332

Distribution Coefficient, logD

3.051

Water Solubility, LogSw

-4.15

Polar Surface Area

81.614

Acid Dissociation Constant (pKa)

6.14

Base Dissociation Constant (pKb)

2.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

D266-0498 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D

References: we are preparing a list of scientific research reports with D266-0498 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D266-0498?
Check Price and Availability of D266-0498, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D266-0498 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D266-0498
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D266-0498
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D266-0498 available by request