D268-0319 Screening compound: N-[4-(1H-1,3-benzodiazol-2-yl)-1,2,5-oxadiazol-3-yl]-4-tert-butylbenzamide

D268-0319 Screening compound: N-[4-(1H-1,3-benzodiazol-2-yl)-1,2,5-oxadiazol-3-yl]-4-tert-butylbenzamide
D268-0319 Screening compound: N-[4-(1H-1,3-benzodiazol-2-yl)-1,2,5-oxadiazol-3-yl]-4-tert-butylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D268-0319
N-[4-(1H-1,3-benzodiazol-2-yl)-1,2,5-oxadiazol-3-yl]-4-tert-butylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D268-0319

Molecular Formula

C20H19N5O2 (C20 H19 N5 O2)

Compound Name

N-[4-(1H-1,3-benzodiazol-2-yl)-1,2,5-oxadiazol-3-yl]-4-tert-butylbenzamide

IUPAC name

N-[4-(1H-13-benzodiazol-2-yl)-125-oxadiazol-3-yl]-4-tert-butylbenzamide

SMILES

CC(C)(C)c(cc1)ccc1C(Nc1nonc1-c1nc(cccc2)c2[nH]1)=O

InChI

InChI=1S/C20H19N5O2/c1-20(2,3)13-10-8-12(9-11-13)19(26)23-18-16(24-27-25-18)17-21-14-6-4-5-7-15(14)22-17/h4-11H,1-3H3,(H,21,22)(H,23,25,26)

InChI Key

JNTZMFKURPCXTR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04213845

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.093

Distribution Coefficient, logD

4.882

Water Solubility, LogSw

-4.95

Polar Surface Area

79.377

Acid Dissociation Constant (pKa)

7.61

Base Dissociation Constant (pKb)

3.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

D268-0319 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Human GPCR Annotated Library (5539 compounds)

Proline Kinase Library (2105 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D268-0319 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D268-0319?
Check Price and Availability of D268-0319, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D268-0319 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D268-0319
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D268-0319
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D268-0319 available by request