D268-0444 Screening compound: N-(4-chlorophenyl)-6-(morpholin-4-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine

D268-0444 Screening compound: N-(4-chlorophenyl)-6-(morpholin-4-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine
D268-0444 Screening compound: N-(4-chlorophenyl)-6-(morpholin-4-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D268-0444
N-(4-chlorophenyl)-6-(morpholin-4-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D268-0444

Molecular Formula

C14H13ClN6O2 (C14 H13 ClN6 O2)

Compound Name

N-(4-chlorophenyl)-6-(morpholin-4-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine

IUPAC name

N-(4-chlorophenyl)-6-(morpholin-4-yl)-[125]oxadiazolo[34-b]pyrazin-5-amine

SMILES

Clc(cc1)ccc1Nc1nc2nonc2nc1N1CCOCC1

InChI

InChI=1S/C14H13ClN6O2/c15-9-1-3-10(4-2-9)16-13-14(21-5-7-22-8-6-21)18-12-11(17-13)19-23-20-12/h1-4H,5-8H2,(H,16,17,19)

InChI Key

MRFLBLOWOUVMLJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00400236

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

332.75

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.660

Distribution Coefficient, logD

3.660

Water Solubility, LogSw

-4.13

Polar Surface Area

76.288

Acid Dissociation Constant (pKa)

13.00

Base Dissociation Constant (pKb)

-1.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

D268-0444 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Immune system
Targets:
  • Others
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D268-0444 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D268-0444?
Check Price and Availability of D268-0444, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D268-0444 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D268-0444
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D268-0444
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D268-0444 available by request