D268-0482 Screening compound: N-[4-(piperidine-1-carbonyl)phenyl]-2-[2-(1,3-thiazol-5-yl)-1H-1,3-benzodiazol-1-yl]acetamide

D268-0482 Screening compound: N-[4-(piperidine-1-carbonyl)phenyl]-2-[2-(1,3-thiazol-5-yl)-1H-1,3-benzodiazol-1-yl]acetamide
D268-0482 Screening compound: N-[4-(piperidine-1-carbonyl)phenyl]-2-[2-(1,3-thiazol-5-yl)-1H-1,3-benzodiazol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D268-0482
N-[4-(piperidine-1-carbonyl)phenyl]-2-[2-(1,3-thiazol-5-yl)-1H-1,3-benzodiazol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D268-0482

Molecular Formula

C24H23N5O2S (C24 H23 N5 O2 S)

Compound Name

N-[4-(piperidine-1-carbonyl)phenyl]-2-[2-(1,3-thiazol-5-yl)-1H-1,3-benzodiazol-1-yl]acetamide

IUPAC name

N-[4-(piperidine-1-carbonyl)phenyl]-2-[2-(13-thiazol-5-yl)-1H-13-benzodiazol-1-yl]acetamide

SMILES

O=C(Cn1c(-c2cncs2)nc2c1cccc2)Nc(cc1)ccc1C(N1CCCCC1)=O

InChI

InChI=1S/C24H23N5O2S/c30-22(26-18-10-8-17(9-11-18)24(31)28-12-4-1-5-13-28)15-29-20-7-3-2-6-19(20)27-23(29)21-14-25-16-32-21/h2-3,6-11,14,16H,1,4-5,12-13,15H2,(H,26,30)

InChI Key

GFDKXVCZDDKZOA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06017018

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.777

Distribution Coefficient, logD

3.776

Water Solubility, LogSw

-3.80

Polar Surface Area

59.791

Acid Dissociation Constant (pKa)

10.24

Base Dissociation Constant (pKb)

2.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

D268-0482 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D268-0482 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D268-0482?
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What is the minimum amount of D268-0482 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D268-0482
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D268-0482
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D268-0482 available by request