D269-0289 Screening compound: 2-(4-chloro-3,5-dimethylphenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]acetamide

D269-0289 Screening compound: 2-(4-chloro-3,5-dimethylphenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]acetamide
D269-0289 Screening compound: 2-(4-chloro-3,5-dimethylphenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D269-0289
2-(4-chloro-3,5-dimethylphenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D269-0289

Molecular Formula

C18H15ClFN3O2S (C18 H15 ClFN3 O2 S)

Compound Name

2-(4-chloro-3,5-dimethylphenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]acetamide

IUPAC name

2-(4-chloro-35-dimethylphenoxy)-N-[3-(4-fluorophenyl)-124-thiadiazol-5-yl]acetamide

SMILES

Cc1cc(OCC(Nc2nc(-c(cc3)ccc3F)ns2)=O)cc(C)c1Cl

InChI

InChI=1S/C18H15ClFN3O2S/c1-10-7-14(8-11(2)16(10)19)25-9-15(24)21-18-22-17(23-26-18)12-3-5-13(20)6-4-12/h3-8H,9H2,1-2H3,(H,21,22,23,24)

InChI Key

UXXVAIHCNOZQRR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08549470

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.85

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.626

Distribution Coefficient, logD

5.626

Water Solubility, LogSw

-6.12

Polar Surface Area

51.203

Acid Dissociation Constant (pKa)

10.77

Base Dissociation Constant (pKb)

-5.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

D269-0289 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D269-0289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D269-0289?
Check Price and Availability of D269-0289, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D269-0289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D269-0289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D269-0289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D269-0289 available by request