D269-0305 Screening compound: 2-(4-fluorophenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]butanamide

D269-0305 Screening compound: 2-(4-fluorophenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]butanamide
D269-0305 Screening compound: 2-(4-fluorophenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D269-0305
2-(4-fluorophenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D269-0305

Molecular Formula

C18H15F2N3O2S (C18 H15 F2 N3 O2 S)

Compound Name

2-(4-fluorophenoxy)-N-[3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl]butanamide

IUPAC name

2-(4-fluorophenoxy)-N-[3-(4-fluorophenyl)-124-thiadiazol-5-yl]butanamide

SMILES

CCC(C(Nc1nc(-c(cc2)ccc2F)ns1)=O)Oc(cc1)ccc1F

InChI

InChI=1S/C18H15F2N3O2S/c1-2-15(25-14-9-7-13(20)8-10-14)17(24)22-18-21-16(23-26-18)11-3-5-12(19)6-4-11/h3-10,15H,2H2,1H3,(H,21,22,23,24)/t15-/m0/s1

InChI Key

WPWLUJDWGZPJKC-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD08549592

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.959

Distribution Coefficient, logD

4.958

Water Solubility, LogSw

-4.57

Polar Surface Area

50.589

Acid Dissociation Constant (pKa)

10.32

Base Dissociation Constant (pKb)

-5.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

D269-0305 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

CNS targets activity set (6557 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D269-0305 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D269-0305?
Check Price and Availability of D269-0305, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D269-0305 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D269-0305
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D269-0305
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D269-0305 available by request