D274-0014 Screening compound: N-[4-({[1-(2-PYRIMIDINYL)-4-PIPERIDYL]AMINO}SULFONYL)PHENYL]ACETAMIDE

D274-0014 Screening compound: N-[4-({[1-(2-PYRIMIDINYL)-4-PIPERIDYL]AMINO}SULFONYL)PHENYL]ACETAMIDE
D274-0014 Screening compound: N-[4-({[1-(2-PYRIMIDINYL)-4-PIPERIDYL]AMINO}SULFONYL)PHENYL]ACETAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound D274-0014
N-[4-({[1-(2-PYRIMIDINYL)-4-PIPERIDYL]AMINO}SULFONYL)PHENYL]ACETAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D274-0014

Molecular Formula

C17H21N5O3S (C17 H21 N5 O3 S)

Compound Name

N-[4-({[1-(2-PYRIMIDINYL)-4-PIPERIDYL]AMINO}SULFONYL)PHENYL]ACETAMIDE

IUPAC name

N-(4-{[1-(pyrimidin-2-yl)piperidin-4-yl]sulfamoyl}phenyl)acetamide

SMILES

CC(Nc(cc1)ccc1S(NC(CC1)CCN1c1ncccn1)(=O)=O)=O

InChI

InChI=1S/C17H21N5O3S/c1-13(23)20-14-3-5-16(6-4-14)26(24,25)21-15-7-11-22(12-8-15)17-18-9-2-10-19-17/h2-6,9-10,15,21H,7-8,11-12H2,1H3,(H,20,23)

InChI Key

KVQURGMMLYVMTJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14816357

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.45

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.802

Distribution Coefficient, logD

1.801

Water Solubility, LogSw

-2.59

Polar Surface Area

86.820

Acid Dissociation Constant (pKa)

10.53

Base Dissociation Constant (pKb)

8.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.29

D274-0014 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with D274-0014 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D274-0014?
Check Price and Availability of D274-0014, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D274-0014 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D274-0014
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D274-0014
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D274-0014 available by request