D274-0132 Screening compound: 1-(4-chlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidine-4-thione

D274-0132 Screening compound: 1-(4-chlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidine-4-thione
D274-0132 Screening compound: 1-(4-chlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidine-4-thione alternative view

Chemical Structure Depiction of ChemDiv screening compound D274-0132
1-(4-chlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidine-4-thione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D274-0132

Molecular Formula

C11H7ClN4S (C11 H7 ClN4 S)

Compound Name

1-(4-chlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidine-4-thione

IUPAC name

1-(4-chlorophenyl)-1H4H5H-pyrazolo[34-d]pyrimidine-4-thione

SMILES

S=C1NC=Nc2c1cnn2-c(cc1)ccc1Cl

InChI

InChI=1S/C11H7ClN4S/c12-7-1-3-8(4-2-7)16-10-9(5-15-16)11(17)14-6-13-10/h1-6H,(H,13,14,17)

InChI Key

CZGVRFHZDOOIOU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11588558

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

262.72

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.641

Distribution Coefficient, logD

2.569

Water Solubility, LogSw

-3.73

Polar Surface Area

36.803

Acid Dissociation Constant (pKa)

8.15

Base Dissociation Constant (pKb)

4.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

D274-0132 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D274-0132 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D274-0132?
Check Price and Availability of D274-0132, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D274-0132 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D274-0132
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D274-0132
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D274-0132 available by request