D274-0223 Screening compound: N-[2-(4-methylphenyl)-2H-1,2,3-benzotriazol-5-yl]pyrazine-2-carboxamide

D274-0223 Screening compound: N-[2-(4-methylphenyl)-2H-1,2,3-benzotriazol-5-yl]pyrazine-2-carboxamide
D274-0223 Screening compound: N-[2-(4-methylphenyl)-2H-1,2,3-benzotriazol-5-yl]pyrazine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D274-0223
N-[2-(4-methylphenyl)-2H-1,2,3-benzotriazol-5-yl]pyrazine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D274-0223

Molecular Formula

C18H14N6O (C18 H14 N6 O)

Compound Name

N-[2-(4-methylphenyl)-2H-1,2,3-benzotriazol-5-yl]pyrazine-2-carboxamide

IUPAC name

N-[2-(4-methylphenyl)-2H-123-benzotriazol-5-yl]pyrazine-2-carboxamide

SMILES

Cc(cc1)ccc1-n1nc(cc(cc2)NC(c3nccnc3)=O)c2n1

InChI

InChI=1S/C18H14N6O/c1-12-2-5-14(6-3-12)24-22-15-7-4-13(10-16(15)23-24)21-18(25)17-11-19-8-9-20-17/h2-11H,1H3,(H,21,25)

InChI Key

KEOUPEHKMBUZSC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05244916

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

330.35

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.005

Distribution Coefficient, logD

2.962

Water Solubility, LogSw

-3.09

Polar Surface Area

65.929

Acid Dissociation Constant (pKa)

8.38

Base Dissociation Constant (pKb)

0.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

D274-0223 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with D274-0223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D274-0223?
Check Price and Availability of D274-0223, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D274-0223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D274-0223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D274-0223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D274-0223 available by request