D278-0110 Screening compound: 4-(4-ethylpiperazin-1-yl)-2-methyl-6-phenylpyrimidine

D278-0110 Screening compound: 4-(4-ethylpiperazin-1-yl)-2-methyl-6-phenylpyrimidine
D278-0110 Screening compound: 4-(4-ethylpiperazin-1-yl)-2-methyl-6-phenylpyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0110
4-(4-ethylpiperazin-1-yl)-2-methyl-6-phenylpyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0110

Molecular Formula

C17H22N4 (C17 H22 N4)

Compound Name

4-(4-ethylpiperazin-1-yl)-2-methyl-6-phenylpyrimidine

IUPAC name

4-(4-ethylpiperazin-1-yl)-2-methyl-6-phenylpyrimidine

SMILES

CCN(CC1)CCN1c1nc(C)nc(-c2ccccc2)c1

InChI

InChI=1S/C17H22N4/c1-3-20-9-11-21(12-10-20)17-13-16(18-14(2)19-17)15-7-5-4-6-8-15/h4-8,13H,3,9-12H2,1-2H3

InChI Key

ULRGWAXIVWOFBI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09982329

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

282.39

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.514

Distribution Coefficient, logD

2.826

Water Solubility, LogSw

-3.48

Polar Surface Area

24.604

Acid Dissociation Constant (pKa)

23.12

Base Dissociation Constant (pKb)

7.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.20

D278-0110 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with D278-0110 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0110?
Check Price and Availability of D278-0110, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0110 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0110
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0110
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0110 available by request