D278-0123 Screening compound: 2,4-dimethyl-6-(4-phenylpiperazin-1-yl)pyrimidine

D278-0123 Screening compound: 2,4-dimethyl-6-(4-phenylpiperazin-1-yl)pyrimidine
D278-0123 Screening compound: 2,4-dimethyl-6-(4-phenylpiperazin-1-yl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0123
2,4-dimethyl-6-(4-phenylpiperazin-1-yl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0123

Molecular Formula

C16H20N4 (C16 H20 N4)

Compound Name

2,4-dimethyl-6-(4-phenylpiperazin-1-yl)pyrimidine

IUPAC name

24-dimethyl-6-(4-phenylpiperazin-1-yl)pyrimidine

SMILES

Cc1cc(N(CC2)CCN2c2ccccc2)nc(C)n1

InChI

InChI=1S/C16H20N4/c1-13-12-16(18-14(2)17-13)20-10-8-19(9-11-20)15-6-4-3-5-7-15/h3-7,12H,8-11H2,1-2H3

InChI Key

FFEPQLUVUGCWMC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09982331

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

268.36

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.128

Distribution Coefficient, logD

3.106

Water Solubility, LogSw

-2.88

Polar Surface Area

24.405

Acid Dissociation Constant (pKa)

22.92

Base Dissociation Constant (pKb)

6.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

D278-0123 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Fragments Library (11262 compounds)

GPCR Targeted Library (31838 compounds)

STING Agonist Library (5895 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Immune system
Structure:
  • Fragments
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D278-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0123?
Check Price and Availability of D278-0123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0123 available by request