D278-0241 Screening compound: N-(2,6-dimethylphenyl)-6-phenylpyrimidin-4-amine

D278-0241 Screening compound: N-(2,6-dimethylphenyl)-6-phenylpyrimidin-4-amine
D278-0241 Screening compound: N-(2,6-dimethylphenyl)-6-phenylpyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0241
N-(2,6-dimethylphenyl)-6-phenylpyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0241

Molecular Formula

C18H17N3 (C18 H17 N3)

Compound Name

N-(2,6-dimethylphenyl)-6-phenylpyrimidin-4-amine

IUPAC name

N-(26-dimethylphenyl)-6-phenylpyrimidin-4-amine

SMILES

Cc1cccc(C)c1Nc1ncnc(-c2ccccc2)c1

InChI

InChI=1S/C18H17N3/c1-13-7-6-8-14(2)18(13)21-17-11-16(19-12-20-17)15-9-4-3-5-10-15/h3-12H,1-2H3,(H,19,20,21)

InChI Key

GOZUIRLNPOCKPQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD26967646

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

275.35

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.606

Distribution Coefficient, logD

4.511

Water Solubility, LogSw

-4.44

Polar Surface Area

27.861

Acid Dissociation Constant (pKa)

18.80

Base Dissociation Constant (pKb)

6.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

D278-0241 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases
  • Proteases
  • Kinases
  • Others

References: we are preparing a list of scientific research reports with D278-0241 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0241?
Check Price and Availability of D278-0241, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0241 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0241
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0241
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0241 available by request