D278-0276 Screening compound: N-(2,5-dimethylphenyl)-2-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

D278-0276 Screening compound: N-(2,5-dimethylphenyl)-2-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine
D278-0276 Screening compound: N-(2,5-dimethylphenyl)-2-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0276
N-(2,5-dimethylphenyl)-2-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0276

Molecular Formula

C16H19N3 (C16 H19 N3)

Compound Name

N-(2,5-dimethylphenyl)-2-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

IUPAC name

N-(25-dimethylphenyl)-2-methyl-5H6H7H-cyclopenta[d]pyrimidin-4-amine

SMILES

Cc1cc(Nc2nc(C)nc3c2CCC3)c(C)cc1

InChI

InChI=1S/C16H19N3/c1-10-7-8-11(2)15(9-10)19-16-13-5-4-6-14(13)17-12(3)18-16/h7-9H,4-6H2,1-3H3,(H,17,18,19)

InChI Key

KCXXEYOXEXLKCP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09982462

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

253.35

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

3.637

Distribution Coefficient, logD

2.408

Water Solubility, LogSw

-3.78

Polar Surface Area

29.064

Acid Dissociation Constant (pKa)

15.17

Base Dissociation Constant (pKb)

8.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

D278-0276 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with D278-0276 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0276?
Check Price and Availability of D278-0276, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0276 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0276
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0276
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0276 available by request