D278-0319 Screening compound: N-(2-fluorophenyl)-2-(methylsulfanyl)-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

D278-0319 Screening compound: N-(2-fluorophenyl)-2-(methylsulfanyl)-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine
D278-0319 Screening compound: N-(2-fluorophenyl)-2-(methylsulfanyl)-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0319
N-(2-fluorophenyl)-2-(methylsulfanyl)-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0319

Molecular Formula

C14H14FN3S (C14 H14 FN3 S)

Compound Name

N-(2-fluorophenyl)-2-(methylsulfanyl)-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine

IUPAC name

N-(2-fluorophenyl)-2-(methylsulfanyl)-5H6H7H-cyclopenta[d]pyrimidin-4-amine

SMILES

CSc1nc(Nc(cccc2)c2F)c(CCC2)c2n1

InChI

InChI=1S/C14H14FN3S/c1-19-14-17-11-8-4-5-9(11)13(18-14)16-12-7-3-2-6-10(12)15/h2-3,6-7H,4-5,8H2,1H3,(H,16,17,18)

InChI Key

ZPROPXGHQXBPSQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD26967648

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

275.35

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.086

Distribution Coefficient, logD

3.993

Water Solubility, LogSw

-4.23

Polar Surface Area

28.173

Acid Dissociation Constant (pKa)

14.78

Base Dissociation Constant (pKb)

6.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

D278-0319 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Fragments Library (11262 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Structure:
  • Fragments
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D278-0319 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0319?
Check Price and Availability of D278-0319, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0319 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0319
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0319
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0319 available by request