D278-0325 Screening compound: N-(4-fluorophenyl)-2-(methylsulfanyl)-6-phenylpyrimidin-4-amine

D278-0325 Screening compound: N-(4-fluorophenyl)-2-(methylsulfanyl)-6-phenylpyrimidin-4-amine
D278-0325 Screening compound: N-(4-fluorophenyl)-2-(methylsulfanyl)-6-phenylpyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0325
N-(4-fluorophenyl)-2-(methylsulfanyl)-6-phenylpyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0325

Molecular Formula

C17H14FN3S (C17 H14 FN3 S)

Compound Name

N-(4-fluorophenyl)-2-(methylsulfanyl)-6-phenylpyrimidin-4-amine

IUPAC name

N-(4-fluorophenyl)-2-(methylsulfanyl)-6-phenylpyrimidin-4-amine

SMILES

CSc1nc(Nc(cc2)ccc2F)cc(-c2ccccc2)n1

InChI

InChI=1S/C17H14FN3S/c1-22-17-20-15(12-5-3-2-4-6-12)11-16(21-17)19-14-9-7-13(18)8-10-14/h2-11H,1H3,(H,19,20,21)

InChI Key

LJZZWKXEJDMUQI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09058031

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

311.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.386

Distribution Coefficient, logD

5.373

Water Solubility, LogSw

-5.67

Polar Surface Area

26.740

Acid Dissociation Constant (pKa)

17.30

Base Dissociation Constant (pKb)

5.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

D278-0325 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antiviral Annotated Library (21441 compounds)

CNS Targets (44014 compounds)

CNS targets activity set (6557 compounds)

Human Receptors Annotated Library (5376 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Epigenetic

References: we are preparing a list of scientific research reports with D278-0325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0325?
Check Price and Availability of D278-0325, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0325 available by request